Xiaoxi (Sofie) Wei is an award-winning American entrepreneur and inventor in the area of biomimetic nanoscience and biopreservation in Regenerative Medicine. Being persistent in her life vision to enable “on-demand organs” from a very young age, she pursued her scientific endeavor in biomimetic Chemistry at SUNY Buffalo, earning her doctorate. Inheriting the entrepreneurial spirit from her family, she successfully managed $8M in engineering projects while completing her Ph.D. Then she founded X-Therma in the San Francisco Bay Area in Oct 2014 to bring lab innovation to patients. Dr. Wei is the inventor of X-Therma’s core technologies based on biomimetic hyper-effective ice prevention materials and devices, resulting in 17 issued global patents. She has served as principal investigator or co-PI of 12 national and international innovation research grants with accumulated value exceeding $14M USD from DoD, NSF, NIH, CIRM, EU etc. She has led the X-Therma research endeavors at The Molecular Foundry, Lawrence Berkeley National Laboratory 2015-2024. She serves as a healthcare advisor for the UC Regents working group on innovation transfer and entrepreneurship, is a scientific advisor for Life Extension Foundation, and was the Vice Chair of the Younger Chemists Committee of the American Chemical Society (ACS), and Cal ACS Executive Committee Member. She is currently a distinguished member of the RULEBREAKER Society, in Germany.