He conducts basic and preclinical study by joint research with professional external research institutes and pursues the acquisition of drug item approvals for each indication like Alzheimer's disease, obesity, stroke, spinal cord injury, traumatic brain injury etc. He is famous for global academic field about control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum and GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease and obesity.