Dr. Lepore is a seasoned biopharma leader who currently serves as CEO of ProFound Therapeutics and CEO-Partner at Flagship Pioneering. Before ProFound, he spent 17 years at GlaxoSmithKline, where he most recently served as Senior Vice President, Head of Research and led a large R&D organization of scientists and physicians focused on leveraging the science of immunology, human genetics, and genomics to identify novel drug targets, discover new therapeutic molecules, and demonstrate proof of mechanism in clinical studies. Before joining the biopharma industry, he was a faculty member in the Division of Cardiovascular Medicine at the University of Pennsylvania, where his lab investigated the transcription regulation of cardiovascular development. Dr. Lepore received his B.S. in Biology from the University of Scranton and his M.D. from Harvard Medical School. He completed his residency in internal medicine and cardiology at Massachusetts General Hospital and his post-doctoral training at the Harvard School of Public Health.