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Frank Nestle

Frank Nestle, MD

Partner and CEO of 3DC
Deerfield Management
Frank Nestle, M.D., FMedSci, is a Partner on the Deerfield Therapeutics team and the Chief Executive Officer of Deerfield Therapeutic Discovery and Development (3DC). His focus is on creating the next generation of therapeutics companies and advancing early-stage therapeutics from scientific discovery through preclinical stages to clinical proof of concept. Prior to joining Deerfield in 2024, Dr. Nestle served as the Global Head of Research and Chief Scientific Officer at Sanofi, where he oversaw all research platforms and therapeutic areas, including Immunology & Inflammation, Oncology, Neuroscience, Rare Diseases, and Genomic Medicine. He has also held leadership roles in several academic and professional organizations and served on the boards of several private companies. With over 220 scientific articles to his name, published in prestigious journals such as Nature, Nature Medicine, Cell, the New England Journal of Medicine, The Lancet, the Journal of Clinical Investigation, and the Journal of Experimental Medicine, Dr. Nestle has made significant contributions to the field. Dr. Nestle holds an M.D. from the Julius Maximilian University of Würzburg and is a Fellow of the UK Academy of Medical Sciences.
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