SPOC Proteomics is a deep-tech life sciences startup that has developed a transformative new proteomic biosensor platform termed sensor-integrated proteome-on-chip (SPOC). SPOC is the world’s first and only platform that provides simultaneous quantitative, qualitative, and kinetic data in a single assay at scale, to support drug and vaccine development, biomarker discovery, and diagnostics. SPOC enables up to 2400 unique proteins per biosensor, for simultaneous analysis using surface plasmon resonance (SPR) and up to 10,000 protein targets for mass spectrometry. SPOC chip proteins are produced in ~4 h directly from DNA with cell-free human lysate and simultaneously captured directly onto biosensors. This unique production method circumvents challenges and expense of traditional recombinant protein workflows, reducing costs 10-100x and decreasing production time. Our mission is to democratize high-throughput kinetic proteomic screens and facilitate early disease detection.