KAHR Bio
Monday, June 03, 2024
Company Presentation
Oncology
Company Presentation Theater 1
KAHR is a clinical-stage oncology company developing novel, dual-targeting fusion proteins that are engineered to activate both the innate and the adaptive immune systems and localize that response in the tumor microenvironment. KAHR's products are designed to be highly specific, capable of both unblocking key immunosuppressive mechanisms and simultaneously activating downstream signals that stimulate key immune cells.
KAHR's lead product candidate, DSP107, selectively targets CD47 and 4-1BB to overcome the safety limitations of first generation products aimed at these targets. DSP107 has shown deep and durable responses in both 2L/3L NSCLC and 3L MSS CRC when combined with atezolizumab, and complete responses in 2L MDS when combined with azacitidine. We are also developing DSP502 (PVR x PD-L1 targeting fusion protein) and DSP216 (HLA-G x CD47 targeting fusion protein) which are in preclinical development.
Company Website:
https://kahrbio.com/
Lead Product in Development:
DSP107 (CD47 x 4-1BB fusion protein)
Number Of Unlicensed Products (For Which You Are Seeking Partners):
Three
Company HQ City
Modi'in Makabim-Re'ut
Company HQ State
Israel
Company HQ Country
Israel
CEO/Top Company Official
Yaron Pereg
Development Phase of Primary Product
Phase II
Primary Speaker