This session dives into Biopharma 4.0, exploring how flexible, multimodal and continuous manufacturing is enabled through platform adaptation and facility/automation design. We'll examine strategy and a conceptual facility design based on a platform that enables multimodal production and seamlessly converts batch to continuous manufacturing. The discussion will focus on best practices for achieving minimal disruption during platform adoption, and the transition from multimodal batch production to continuous manufacturing in a smaller facility through integrated and intelligent automation.