Startups and VCs have a symbiotic relationship that can sometimes experience many ups and downs. What happens when startups work with venture investors from the beginning to create a new company around a technology or asset, and how difficult is it for these companies to become independent following their launch out of stealth? With deep benches of scientists, shared office infrastructure, incubators, and extensive industry experience, many VC firms have a breadth of assets that science-driven startups need. Hear from two high profile venture firms and the leaders of two companies they helped form about the pros, challenges and pitfalls of company formation efforts led by VCs.