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Oncology Investment Themes: Where is the Market Putting its Money?

June 16, 2025
Breakout Session
Oncology
Across therapeutic areas, oncology is richest in depth of pipeline and variety of potential modalities/mechanisms of action. Of nearly 200 different products in Phase 3 alone, small molecules are now in the minority (45%). Emerging modalities, such as antibody-drug conjugates, cell therapies, oncolytic viruses, cancer vaccines, and radiopharmaceuticals now make up 15% of the Phase 3 pipeline. But where is financial investment into the oncology pipeline going, and how does it differ between venture funding, M&A/licensing, and IPOs? As recently as 2019, all M&A in oncology was for small molecules or monoclonal antibodies. However, over the past 24 months, 50% of biotech acquisitions were in cell therapy, antibody-drug conjugates, radiopharmaceuticals, or cancer vaccines. Using industry pipeline and deal data from the past five years, panelists will take an in-depth look at the financing and deals environment in the oncology drug market to understand past trends and discuss where the industry may be heading.
Moderator
Ashwin Singhania
Partner
Ernst & Young
Speakers
Liz Barrett
CEO
Urogen
Christopher Mortko, PhD, MBA
Vice President, Business Development & Licensing
Merck
Dan Switzer
Head of US Oncology Business Division
Daiichi Sankyo
Jack Wu, PhD, MBA
Senior Director, Search & Evaluation, Global Oncology
Takeda

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