Biotechnology supply chains are inherently global, spanning research, development, manufacturing, distribution, and skilled workforce networks across multiple countries. This interdependence has driven innovation and improved access to care, but it also exposes critical vulnerabilities—ranging from geopolitical instability to climate-related disruptions. This panel will explore how international cooperation can enhance supply chain resilience while spotlighting the importance of strong national strategies that build local capacity and reinforce key links in the global system. Panelists will share insights on mitigating disruptions, fostering innovation, and creating national value while contributing to a secure, globally integrated healthcare ecosystem.