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AstraGenomics

June 16, 2025
Company Presentation
Cell and Gene Therapy and Genome Editing
AstraGenomics is a biotechnology company pioneering innovative genome editing technologies. Empowered by a systematic platform integrating computational biology and lab automation, the company has developed a diversified tool library for large fragment gene writing and miniature nuclease-based gene editing. The company has developed gene writing technology using DNA transposon and retrotransposon system, which can integrate up to 15kb gene fragment. Also, we have developed TnpB miniature nuclease for high fidelity and specificity gene editing across various cell types and species. We are using our proprietary technologies to explore in vivo and ex vivo gene therapy, in the field of genetic diseases and cancer. At the same time, we are partnering with industrial leaders in multiple fields including CGT, agriculture and biomanufacturing, to innovate these fields with ground-breaking genome editing technologies.
AstraGenomics
Company HQ City: Beijing
Company HQ State: Beijing
Company HQ Country: China
Year Founded: 2022
Lead Product in Development: We have developed gene writing technologies with DNA transposons and Retrotransposons. Our technology has displayed the capacity to integrate up to 15kb gene fragment into the genome, with high efficiency across multiple cell types. We are using our proprietary gene writing technology to develop non-viral CAR-T, and have exhibited good efficacy in animal model. We are also developing in vivo CAR-T solution from the transposon based system.

CEO

Chengxi Shi

Development Phase of Lead Product

Pre-Clinical

Number of Unlicensed Products Looking for Licensing

2

When you expect your next catalyst update?

The next catalyst update will be the animal model validation and IND enabling of in vivo large fragment gene writing for CAR-T and selected genetic disease indications.

What is your next catalyst (value inflection) update?

2026.06
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Primary Speaker
Chengxi Shi
Chengxi Shi, PhD
CEO & Co-founder
AstraGenomics

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