Apertor Pharmaceuticals, Inc.
June 16, 2025
Company Presentation

Apertor Pharmaceuticals is creating novel molecular glues for therapeutic applications in oncology. At Apertor we have developed a new class of therapeutics to address one of the toughest challenges in drug discovery — selective disruption of disease-causing protein-protein interactions (PPIs). Apertor’s Interceptors are designed to selectively disrupt protein complexes via proximity induction by recruiting an abundantly expressed protein naturally found in cancerous cells patient’s own proteins to safely and effectively block PPIs . Using our synthetic biology platform technology to invent and develop proprietary Interceptors, Apertor’s robust pipeline is unlocking new treatment possibilities for cancer patients.
Apertor has identified its first development candidate targeting the mTORC1/4E-BP1 complex for the treatment of solid tumors in Q125, and has built a robust pipeline of additional programs addressing high-value oncology targets. Apertor raised $50M in Series A financing.

Company HQ City:
Alameda
Company HQ State:
CA
Company HQ Country:
United States
Year Founded:
2020
Lead Product in Development:
mTOR/4E-BP1 inhibitor
CEO
Edmund Graziani PhD
Development Phase of Lead Product
Pre-Clinical
Number of Unlicensed Products Looking for Licensing
3
When you expect your next catalyst update?
IND submission
What is your next catalyst (value inflection) update?
12/2026
Primary Speaker