Valley Fever Solutions
- Biotech or pharma, therapeutic R&D
- Biotech or pharma, animal health
Nikkomycin Z (nikZ) is 30x more effective in a new formulation. New IP extends value. NikZ is fungicidal against Coccidioides (valley fever, VF) and in the new protocol clears severe VF in naturally infected dogs. NikZ suppresses other important fungi
Valley Fever Solutions (VFS) is focused first on a lead compound to eliminate Coccidioides (valley fever, VF), ready for Phase 2 trials. Formulation targets include QD oral, IV and topical. VFS is looking at new potential therapeutics.
Significantly, oral NikZ sterilizes VF CNS infection, which we expect to prove quickly in humans as a superior therapy, safer and faster than current therapy for thousands. NikZ should treat essentially all VF infections, saving up to 150 lives and resolving up to 50K VF illnesses. NikZ suppresses virulent Candida albicans in vivo and has low MICs against Candida auris. NikZ suppresses other important fungi such as Mucorales and potentiates other drugs against important fungal infections.
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