Intero Biosystems
- Biotech or pharma, therapeutic R&D
- Other R&D services
Intero Biosystems develops stem cell-derived human intestinal organoids for pre-clinical testing to predict how drugs will behave in humans before entering clinical trials. Spun out of Dr. Jason Spence’s lab at the University of Michigan, our team has created the first stem cell-derived “mini-gut” that replicates the key cell types, spatial architecture, and functions of the human intestine. Our flagship product, GastroScreen, features the intestinal lining along with supporting tissues—functional smooth muscle capable of peristalsis, perfusable blood vessels, and neurons responsive to stimuli—forming a complete, functional mini-organ in a dish. GastroScreen can be used to model both healthy tissue for preclinical toxicity testing and diseased tissue, such as intestinal fibrosis, for efficacy screening.
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