The promise of cell and gene therapy is extraordinary - but so are the challenges of producing it at scale. Manufacturing remains the key barrier to delivering these life-changing therapies to patients globally. Now, a new wave of technologies is transforming that reality. Automation, AI, digital twins, and advanced analytics are driving consistency, speed, and scalability, while next-generation platforms are enabling closed, modular, and data-driven production systems. This session brings together experts across bioprocess engineering, CDMOs, and CGT innovators to explore how technology is redefining manufacturing economics and accessibility. Panelists will discuss integrating digital process control, predictive analytics, and smart automation to reduce cost of goods, improve reproducibility, and enable global supply at commercial scale. The conversation will also highlight partnerships that blend biotech innovation with tech-driven process excellence to build a sustainable, connected manufacturing ecosystem for the next generation of cell and gene therapies.