This session will explore the critical journey of translating a scientific concept into a viable CNS therapeutic. Industry leaders will discuss the primary challenges and emerging solutions in neuroscience drug development, from initial discoveries to clinical application. Key topics to be discussed include developing disease models with translational relevance, identifying and validating causal therapeutic targets, leveraging biomarkers for patient stratification and defining meaningful trial endpoints, and innovating safe and efficient methods for drug delivery across the blood-brain barrier. Attendees will gain a comprehensive understanding of the current and emerging therapeutic landscape and future directions in bringing novel treatments to patients with neurological disorders.